TYROSINE NITRATION OF A HUMANIZED ANTI-COPYRIGHT MAB DIFFERENTIALLY AFFECTS LIGAND BINDING OF COPYRIGHT AND ITS METABOLITES

Tyrosine nitration of a humanized anti-copyright mAb differentially affects ligand binding of copyright and its metabolites

Tetranitromethane was used to selectively modify tyrosine residues of a humanized anti-copyright mAb (h2E2), under development for the treatment of copyright use disorders.The effect of mild tyrosine nitration on the affinity of copyright and two high affinity copyright metabolites, cocaethylene and benzoylecgonine, was assessed using differential

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A New Perspective of Flexible Clocking Ideology for Driving and Devising Circuits in Emerging Resource-Constrained Applications

Clock is the most important signal in electronic system.In current practice, the dominant clocking style is the fixed-frequency approach.For a given application, the clock signal is only required to work at a few selected frequencies.Moreover, in the process of performing a task, it must not change its frequency.This style has worked well in the pa

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Cognitive Mimetics for Designing Intelligent Technologies

Design mimetics is an important method of creation in technology design.Here, we review design mimetics as a plausible approach to address the problem of how to design generally intelligent technology.We argue that design mimetics can be conceptually divided into Roper Style Saddle three levels based on the source of imitation.Biomimetics focuses o

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